Experimental medicine and integrated pathophysiology: basic and translational research aimed at understanding the mechanisms underlying various human diseases and studying their integrated contribution to the genesis of other disease states, while identifying possible targets for therapy.

Diagnostic, therapeutic and nanomedicine technologies: basic, pre-clinical and clinical research aimed at diagnostic and therapeutic technology, i.e. research using nanomedicine tools/devices and methods, as well as at the development of drugs, diagnostic and therapeutic methods, equipment and their performance and signal processing.

Public health and clinical epidemiology: research in the field of methodology for the design, conduct and analysis of clinical and epidemiological studies and applied research in the areas of prevention and public health, clinical psychology, occupational medicine, forensic medicine and nursing, as well as outcome research and management of health models.

Medical sciences: the study of clinical aspects of both acuteness and comorbidity, frailty and complexity typical of the elderly, as well as of medical diseases in the cardiac, vascular, respiratory, nephro-urological, endocrinological and rheumatological fields. Study of hereditary/rare adult diseases including iron metabolism disorders, anaemias and hereditary metabolic diseases, with a focus on the transition of these diseases from paediatric to adult age.

Oncology and Haematology: research in adult and paediatric oncology and haematology.

Maternal, developmental and gynaecological sciences: research into complex genetic and malformative syndromes, congenital metabolic diseases, midwifery and maternal-fetal medicine, the patho-physiology of pelvic support and the development of innovative therapeutic approaches using cell and gene therapies.

Surgical sciences: research aimed at understanding and improving the management of both general and specialised surgical pathology in the cardiovascular and craniofacial fields also using “augmented surgery” methods through 3D simulations.

Neurosciences: clinical, translational and basic research into neurological and psychiatric diseases, in their aetiopathogenetic, diagnostic and therapeutic aspects, with reference to the identification of biomarkers and the use of innovative therapies also in the field of tissue repair/regeneration, rehabilitation and clinical and hospital psychology.

Digestive Health: it encompasses research in the biological, pathophysiological, translational, health, behavioural and social fields concerning the state of health and disease of the hepato-gastro-enterological system, of whatever aetiology, and the related preventive, as well as therapeutic medical, surgical and transplant related actions. Specific areas of research are also aspects regarding the local and systemic impact of the microbiota and the systemic impact of eating disorders and the inherent dietary measures.

Neuro-Cardio-Respiratory-Health: it includes the integrated research on the interactions between cardiovascular regulatory mechanisms and both central and autonomic nervous system-derived influences. Specific applications include the study of the response to stress, including stress at work; the cardiovascular and systemic effects of sleep quantity and quality disorders (with a key and increasingly important role being played by the study of the systemic effects of sleep-related respiratory changes, such as sleep apnoea) and the cardiovascular and systemic effects of hypoxia, including the study of the effects deriving from the exposure to hypobaric hypoxia at high altitudes, which in itself represents an interesting example of translational medicine capable of offering a “bridging” between pathophysiology and clinical implications